Biology of the Laboratory Mouse

The rapid development of nucleic acid research has resulted in the emergence of a wide variety of techniques associated with such research. The documentation of even some of these techniques in a well-written form is a formidable task. That the editors of this book have succeeded in producing such a fine first volume is a measure of the care they have taken and the calibre of the specialists contributing to the volume. This volume contains a description of techniques connected with "Enzymes of Nucleic Acid Metabolism" and the "Isolation, Preparation and Characterization of Natural and Synthetic Nucleic Acids." Under the first heading are sections dealing with enzymes involved in degradation and synthesis of DNA and RNA as well as a section on enzymes of t-RNA metabolism. The second part of the book is devoted to both RNA and DNA. Each section is divided into various chapters, each of which is concise and informative, with the practical procedures described quite comprehensively. In some chapters a good deal of background information is included with sufficient, up-to-date references to enable the reader to consult the literature profitably for results accruing from the use of the techniques described. This coverage is invaluable to the non-specialist and certainly interesting to those directly involved in nucleic acid research. The reader will also appreciate the author and subject indices included at the end of the book, which cite each author mentioned, as well as list in detail aspects of the subject covered. This book is well worth having as a reference. LOUIS LIM